ARTICLE
- MIT Technology Review
(2023)
eGenesis has started transplanting gene-edited pigs’ hearts into infant baboons—and humans may be next.
The company, based in Cambridge, Massachusetts, has developed a technique that uses the gene-editing tool CRISPR to make around 70 edits to a pig’s genome. These edits should allow the organs to be successfully transplanted into people, the team says. As soon as next year, eGenesis hopes to transplant pig hearts into babies with serious heart defects. The goal is to buy them more time to wait for a human heart…
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Summary:
eGenesis, a company based in Massachusetts, is using gene-editing technology and CRISPR to alter the genomes of pigs in order to transplant their hearts into babies with serious heart defects as soon as next year. The goal of the research is to provide a way for infants with heart defects to buy more time until they can receive a human heart for transplantation.
Keywords: eGenesis, gene-editing,CRISPR,transplantation,pig hearts,infant heart defects
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